Bilberry Extract (25% Anthocyanin)

Food Code: 253611
Bilberry (Vaccinium myrtillus) extract standardized to 25% anthocyanins for eye-comfort, antioxidant and microcirculation-support supplement formulas.
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Bilberry Extract (25% Anthocyanin) is a standardized Vaccinium myrtillus fruit extract for eye-comfort, antioxidant and microcirculation-support supplement formulas. “25% anthocyanins” means anthocyanins account for 25% of the extract weight; for example, 400 mg extract provides about 100 mg anthocyanins. Anthocyanins are the purple/blue polyphenol pigments that give bilberry its strong antioxidant story and make the extract useful in formulas for screen fatigue, ocular-surface comfort and capillary-support concepts.


BenefitTypical study dose*Key human findingsHigh-quality sources
1 Eye strain / “screen fatigue”~240 mg/day for 12 weeksRandomized placebo-controlled trial in near-work/VDT context reported improvements in measures related to eye fatigue/ciliary muscle strain. A useful human signal for eye-comfort positioning; keep claims tied to the study design and dose.Nutrients (MDPI)
2 Dry eye symptomsDaily bilberry extract for 4 weeksSmall randomized placebo-controlled study reported improved tear production (Schirmer’s test) and changes in oxidative-stress/antioxidant markers after 4 weeks.European Review
3 Minor venous circulation (traditional use)Traditional use (EMA)EMA lists bilberry fruit preparations as traditional herbal medicinal products for symptoms of minor venous circulation issues (e.g., heavy/tired legs) and capillary fragility; this provides a recognized traditional-use basis for microcirculation and capillary-support concepts.EMA herbal monograph
Safety profileTypical supplement rangesBilberry is generally well-tolerated and has not been strongly linked to liver injury.LiverTox (NCBI)

*Doses shown refer to the extract used in studies. For a “25% anthocyanins” extract, 240 mg/day corresponds to ~60 mg/day anthocyanins (25% by weight). Extract specifications and bioavailability can vary by manufacturer.



Mechanistic highlights

  1. Anthocyanin antioxidant network: Anthocyanins support redox buffering and may help mitigate oxidative stress discussed in eye-fatigue and ocular-surface contexts.
  2. Microvascular support: Polyphenols may support endothelial function and capillary resilience, aligning with traditional use around capillary fragility/heavy legs.
  3. Ocular surface defense: Antioxidant effects may support ocular-surface homeostasis; clinical evidence is still developing, so use as ocular-comfort support rather than a medical claim.


Safety & practical use

  • Usual supplemental range: Common standardized bilberry-extract regimens fall roughly around 120–480 mg/day; choose targets based on the anthocyanin standardization.
  • Drug interactions: Use caution with anticoagulants/antiplatelet drugs (possible platelet effects); consult a clinician before use.
  • Under 18: Use in children/adolescents is not established due to limited data.
  • Pregnancy/lactation: Avoid unless medically advised (limited human data).


Bilberry Extract (25% Anthocyanin)
Bilberry (Vaccinium myrtillus) extract standardized to 25% anthocyanins for eye-comfort, antioxidant and microcirculation-support supplement formulas.

Bilberry Extract (25% Anthocyanin) is a standardized Vaccinium myrtillus fruit extract for eye-comfort, antioxidant and microcirculation-support supplement formulas. “25% anthocyanins” means anthocyanins account for 25% of the extract weight; for example, 400 mg extract provides about 100 mg anthocyanins. Anthocyanins are the purple/blue polyphenol pigments that give bilberry its strong antioxidant story and make the extract useful in formulas for screen fatigue, ocular-surface comfort and capillary-support concepts.


BenefitTypical study dose*Key human findingsHigh-quality sources
1 Eye strain / “screen fatigue”~240 mg/day for 12 weeksRandomized placebo-controlled trial in near-work/VDT context reported improvements in measures related to eye fatigue/ciliary muscle strain. A useful human signal for eye-comfort positioning; keep claims tied to the study design and dose.Nutrients (MDPI)
2 Dry eye symptomsDaily bilberry extract for 4 weeksSmall randomized placebo-controlled study reported improved tear production (Schirmer’s test) and changes in oxidative-stress/antioxidant markers after 4 weeks.European Review
3 Minor venous circulation (traditional use)Traditional use (EMA)EMA lists bilberry fruit preparations as traditional herbal medicinal products for symptoms of minor venous circulation issues (e.g., heavy/tired legs) and capillary fragility; this provides a recognized traditional-use basis for microcirculation and capillary-support concepts.EMA herbal monograph
Safety profileTypical supplement rangesBilberry is generally well-tolerated and has not been strongly linked to liver injury.LiverTox (NCBI)

*Doses shown refer to the extract used in studies. For a “25% anthocyanins” extract, 240 mg/day corresponds to ~60 mg/day anthocyanins (25% by weight). Extract specifications and bioavailability can vary by manufacturer.



Mechanistic highlights

  1. Anthocyanin antioxidant network: Anthocyanins support redox buffering and may help mitigate oxidative stress discussed in eye-fatigue and ocular-surface contexts.
  2. Microvascular support: Polyphenols may support endothelial function and capillary resilience, aligning with traditional use around capillary fragility/heavy legs.
  3. Ocular surface defense: Antioxidant effects may support ocular-surface homeostasis; clinical evidence is still developing, so use as ocular-comfort support rather than a medical claim.


Safety & practical use

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