Xylooligosaccharide (XOS, 95%)
Food
Code: 253151
Prebiotic XOS 95% for foods/supplements; supports Bifidobacterium, regularity, and gut barrier at low daily doses (≈1–4 g).
Xylooligosaccharide (XOS, 95%) 95% XOS (xylooligosaccharides) is a prebiotic dietary fiber used in foods and supplements to selectively increase beneficial Bifidobacterium and support regularity and gut barrier function.
| Benefit | Typical study dose* | Key human findings | High-quality sources |
|---|---|---|---|
| Gut microbiome support (↑ Bifidobacterium) | ~1.4–2.8 g/day; 2–8 weeks | Consistent bifidogenic effect with good tolerance (little gas/bloating) | RSC Publishing; PubMed |
| Constipation relief | 3–10 g/day; ~4 weeks | Improved stool form and constipation scores; better QoL | PubMed (2023 RCT) |
| Metabolic markers (early signals) | ~4 g/day; 8 weeks | Small improvements in glucose, lipids, oxidative stress in select cohorts | PubMed |
| Immune/endotoxemia modulation | 1–4 g/day; 2–12 weeks | Changes in endotoxemia and immune readouts; stronger with inulin combinations | Cambridge Univ. Press; PubMed Central |
*Dosing ranges compiled from XOS human studies; responses vary by person. Start low and titrate to comfort.
Mechanistic highlights
- Selective fermentation: XOS preferentially nourishes bifidobacteria vs. many commensals.
- Short‑chain fatty acids (SCFAs): Fermentation yields acetate/propionate/butyrate that influence motility, epithelial barrier integrity, and metabolic signaling.
- Endotoxemia/immune tone: Prebiotic shifts can reduce endotoxin exposure and modulate inflammatory parameters (preliminary in healthy adults).
Safety & practical use
- Usual supplemental range: 1–4 g/day with food; many aim ~2 g/day.
- Upper‑dose tolerance: Generally well‑tolerated; sensitive users may experience gas/bloating at higher intakes.
- How to use: Mix into beverages, smoothies, yogurt, or dry mixes. Start ~1 g/day and increase as tolerated to ~2–3 g/day.
- Constipation protocols: Trials used 3–10 g/day for ~4 weeks; titrate upward and reassess after 2–4 weeks.
- Interactions/precautions: Separate from medications by 2–3 hours if concerned; consult if on a low‑FODMAP plan or with GI conditions.
- white to off‑white powder
- Room (25-40C)
- 24 Months from manufacturing or testing date.
- 1000mg - 4000mg
- 2000mg
- 1000mg - 4000mg
- 2000mg
- Add at last step. Avoid temperature above 40C.
- Heat Tolerant
- 0.00 - 0.00
- -
| Test Name | Specification |
|---|---|
| Appearance | Powder |
| Color | White or slightly yellowish |
| Odor | Characteristic |
| Taste | Sweet |
| Foreign matter | No visible foreign matter |
| XOS content (dry basis), % | ≥95.0 |
| XOS2–4 content (dry basis), % | ≥65.0 |
| pH | 3.5–6.0 |
| Moisture, % | ≤5.0 |
| Ash, % | ≤0.3 |
| Total plate count, CFU/g | ≤1000 |
| Coliforms, CFU/g | ≤10 |
| Mold, CFU/g | ≤25 |
| Yeast, CFU/g | ≤25 |
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