Acid-PEG3-PFP ester is widely used in bioconjugation and chemical biology for the modification of biomolecules. Its reactive PFP ester group facilitates efficient coupling with amines, making it valuable for labeling proteins, peptides, and antibodies. This compound is particularly useful in the development of drug delivery systems, where it helps in attaching targeting ligands or therapeutic agents to carriers. Additionally, it plays a role in the synthesis of functionalized polymers and materials for biomedical applications, such as hydrogels or nanoparticles. Its PEG spacer enhances solubility and reduces immunogenicity, making it suitable for in vivo applications. Researchers also utilize it in the preparation of bioconjugates for diagnostic imaging and therapeutic studies.