Niperotidine is primarily used as an H2 receptor antagonist, which makes it effective in reducing stomach acid production. It is commonly applied in the treatment of gastrointestinal conditions such as peptic ulcers, gastroesophageal reflux disease (GERD), and Zollinger-Ellison syndrome. By inhibiting histamine-induced acid secretion in the stomach, it helps alleviate symptoms like heartburn, acid indigestion, and stomach pain. Additionally, it may be used in combination with other medications to enhance its therapeutic effects in managing acid-related disorders. Its role in promoting the healing of ulcers and preventing their recurrence has made it a valuable component in gastroenterology.