“Closest formula-family evidence: a salicylic-acid/LHA/niacinamide/2-oleamido-1,3-octadecanediol/piroctone-olamine/zinc dermocosmetic reduced inflammatory and non-inflammatory acne lesions and was better tolerated than benzoyl peroxide 5%.”
Duo+M Serum (Compare La Roche-Posay Effaclar)
Cosmetics
Code: 127690
Developed to be similar to La Roche-Posay Effaclar Duo+M Serum
Developed to be similar to La Roche-Posay Effaclar Duo+M Serum
Active Ingredients:
2-Oleamido-1,3-Octadecanediol (Ceramide NP)
The product is not produced by La Roche
Use: Use it as a base in any formula.
How to mix: Add various ingredients to the base.
Utilization rate: 90-100%
Product characteristics: liquid gel texture
Solubility: can dissolve with water
Storage: store at room temperature Avoid heat and sunlight, age 2 years.
INCI Name: Aqua/Water/Eau, Glycerin, Dimethicone, Isocetyl Stearate, Niacinamide, Silica, Ammonium Polyacryloyldimethyl Taurate, Oryza Sativa Starch / Rice Starch, Potassium Cetyl Phosphate, Sorbitan Oleate, Zinc Pca, Glyceryl Stearate SE, Isohexadecane, Sodium Hydroxide, Myristyl Myristate, 2-Oleamido-1,3-Octadecanediol, Mannose, Poloxamer 338, Propanediol, Hydroxethoxyphenyl Butanone, Capryloyl Salicylic Acid, Caprylyl Glycol, Citric Acid, Trisodium Ethylenediamine Disuccinate, Maltodextrin, Xanthan Gum, Pentylene Glycol, Polysorbate 80, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Salicylic Acid, Piroctone Olamine
- Room (25-40C)
- 24 Months from manufacturing or testing date. (Current Lot will expire: 04/2028)
- 90.00% - 100.00%
- 100.00%
- Trial formulation must register with FDA before market release
- Avoid heat above 40C
- 4.00 - 7.00
- Dispersible in water, Dispersible in cream or gel base
- Serum
- -
| Test Name | Specification |
|---|---|
| Appearance | White to off-white colored paste |
| Odor | No peculiar odor, characteristics |
| Total Aerobic Microbial Count | < 100 CFU/ml |
| Yeast & Moulds | < 10 CFU/ml |
“Closest combination evidence: topical nicotinamide plus antibacterial adhesive agents and zinc-PCA improved moderate acne as an adjuvant versus placebo; supports niacinamide + zinc-PCA acne benefit, not the exact serum.”
“Niacinamide evidence: topical 4% nicotinamide showed comparable efficacy to clindamycin gel in inflammatory acne; supports niacinamide as an anti-acne/anti-inflammatory component.”
“Capryloyl salicylic acid evidence: lipohydroxy acid formulation showed comedolytic activity in acne-prone subjects; supports pore-unclogging benefit of the LHA ingredient family.”
“Salicylic acid evidence: 0.5% and 2% salicylic acid solutions were reported effective and safe for acne treatment; supports keratolytic/comedolytic acne benefit.”
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