4-Bromo-3-(fluorosulfonyl)benzoic acid
95%
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Used as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in the development of fluorinated compounds. Its fluorosulfonyl group enables selective functionalization in aromatic rings, making it valuable in medicinal chemistry for creating sulfonyl fluoride-based inhibitors. These inhibitors are increasingly used in proteomics and drug discovery due to their ability to covalently bind to active site residues in enzymes. Also employed in the preparation of PET (positron emission tomography) tracers, where the bromine atom facilitates radiolabeling with isotopes like bromine-76 or carbon-11. Its reactivity allows for cross-coupling reactions, expanding its utility in building complex bioactive molecules.
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