Ciproxifan maleate is primarily used in research settings to study the role of histamine H3 receptors in the central nervous system. It acts as a potent and selective antagonist of these receptors, making it a valuable tool for investigating their function in various physiological processes. Researchers utilize it to explore its potential effects on cognitive functions, such as memory and learning, as well as its impact on sleep-wake cycles and attention. Additionally, it is studied for its possible therapeutic applications in neurological disorders, including narcolepsy, ADHD, and Alzheimer's disease, due to its ability to modulate histaminergic activity in the brain. Its application is largely confined to preclinical studies, contributing to a deeper understanding of histamine receptor mechanisms.