Selumetinib sulfate (AZD6244 sulfate)

98%

Reagent Code: #109590
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CAS Number 943332-08-9

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Weight 555.76 g/mol
Formula C₁₇H₁₇BrClFN₄O₇S
inventory_2 Storage & Handling
Storage -20°C, airtight, dry

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Selumetinib sulfate is primarily used in the treatment of certain types of cancer, particularly in patients with neurofibromatosis type 1 (NF1) who have symptomatic, inoperable plexiform neurofibromas. It works by inhibiting the MEK enzyme, which is part of the MAPK/ERK pathway, a signaling pathway that can promote cancer cell growth and survival. By blocking this pathway, selumetinib sulfate helps to reduce tumor size and alleviate symptoms associated with these tumors. It is often prescribed for pediatric patients when surgical removal of the tumors is not feasible. Additionally, ongoing research is exploring its potential efficacy in other cancers, such as melanoma, non-small cell lung cancer, and thyroid cancer, where the MAPK/ERK pathway is dysregulated.

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Size Availability Unit Price Quantity
inventory 50mg
10-20 days ฿9,423.00
Selumetinib sulfate (AZD6244 sulfate)
Selumetinib sulfate is primarily used in the treatment of certain types of cancer, particularly in patients with neurofibromatosis type 1 (NF1) who have symptomatic, inoperable plexiform neurofibromas. It works by inhibiting the MEK enzyme, which is part of the MAPK/ERK pathway, a signaling pathway that can promote cancer cell growth and survival. By blocking this pathway, selumetinib sulfate helps to reduce tumor size and alleviate symptoms associated with these tumors. It is often prescribed for pediatric patients when surgical removal of the tumors is not feasible. Additionally, ongoing research is exploring its potential efficacy in other cancers, such as melanoma, non-small cell lung cancer, and thyroid cancer, where the MAPK/ERK pathway is dysregulated.
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