Lipase A from Aspergillus niger is widely used in various industrial applications due to its ability to catalyze the hydrolysis of fats and oils. In the food industry, it is employed to enhance flavors in cheese and dairy products by breaking down milk fats, contributing to the development of unique taste profiles. It is also utilized in baking to improve dough handling and texture by modifying lipids in flour.

In the detergent industry, this enzyme is a key component in laundry and dishwashing products, where it effectively removes grease and oil stains by breaking down fatty substances. Additionally, Lipase A is used in the production of biodiesel, where it catalyzes the transesterification of vegetable oils or animal fats into fatty acid methyl esters, a sustainable alternative to fossil fuels.

In the pharmaceutical sector, it aids in the synthesis of chiral compounds and active pharmaceutical ingredients, leveraging its specificity and efficiency in organic synthesis. Furthermore, it finds applications in the leather industry for degreasing hides and skins, ensuring a cleaner and more uniform finish. Its versatility and effectiveness make it a valuable enzyme across multiple industries.