N-Propargylmaleimide is widely used in the field of bioconjugation and materials science due to its reactive alkyne group, which allows for efficient click chemistry reactions. It is particularly valuable in the modification of proteins, peptides, and polymers, enabling the attachment of functional groups or labeling molecules for research and diagnostic purposes. In polymer chemistry, it serves as a crosslinking agent to enhance the mechanical properties and stability of materials. Additionally, it is utilized in the synthesis of drug delivery systems, where its reactivity facilitates the creation of targeted and controlled-release formulations. Its application in surface functionalization also makes it suitable for developing biosensors and advanced coatings.