Lipoamide-PEG3-Mal is widely used in bioconjugation and chemical biology for attaching molecules to proteins or peptides. Its lipoamide group allows for specific binding to thiol groups, making it ideal for modifying cysteine residues in proteins. The PEG3 spacer enhances solubility and reduces steric hindrance, ensuring efficient conjugation. This compound is particularly valuable in drug delivery systems, where it helps create stable and targeted conjugates. Additionally, it is utilized in the development of diagnostic probes and biophysical studies, enabling precise labeling and tracking of biomolecules. Its versatility also extends to surface modification of nanoparticles, improving their biocompatibility and functionality for therapeutic applications.