L-Psicose is widely used as a low-calorie sweetener in the food and beverage industry due to its minimal impact on blood sugar levels. It is particularly beneficial for diabetic-friendly products, offering a sweet taste without the associated glycemic response. In the health and wellness sector, it is incorporated into dietary supplements and functional foods aimed at weight management and metabolic health. Additionally, L-Psicose is utilized in the production of baked goods, dairy products, and confectionery to enhance sweetness while reducing calorie content. Its ability to inhibit the formation of advanced glycation end-products (AGEs) also makes it valuable in anti-aging and skin care formulations. In research, it serves as a model compound for studying rare sugars and their metabolic effects.