PD 117519 is primarily utilized in research settings as a selective antagonist for the glycine site on the NMDA receptor. Its application is crucial in studying the role of NMDA receptors in various neurological processes, including synaptic plasticity, learning, and memory. By blocking the glycine site, it helps researchers understand the mechanisms underlying excitotoxicity, which is implicated in neurodegenerative diseases such as Alzheimer's and Parkinson's. Additionally, PD 117519 is used in experimental models to explore potential therapeutic interventions for conditions involving overactivation of NMDA receptors, such as stroke and epilepsy. Its specificity makes it a valuable tool in neuroscience research, aiding in the development of targeted treatments for neurological disorders.