This chemical is primarily used in the synthesis of modified nucleosides, which are essential components in the development of oligonucleotides and nucleic acid analogs. It serves as a key intermediate in the preparation of antisense oligonucleotides, which are used in gene therapy and molecular biology research. The tert-butyldimethylsilyl (TBDMS) group acts as a protecting group for the hydroxyl function during chemical reactions, ensuring selective modification of the nucleoside. This compound is particularly valuable in the synthesis of therapeutic agents targeting genetic disorders, viral infections, and cancer. Its application extends to the production of probes for studying DNA and RNA interactions, as well as in the development of diagnostic tools.