Used primarily in oligonucleotide synthesis, this compound serves as a protected nucleoside building block. It is crucial in the production of modified RNA molecules, particularly in the development of antisense oligonucleotides and siRNA therapeutics. The DMT (dimethoxytrityl) group protects the 5'-hydroxyl during synthesis, while the 2'-O-methyl modification enhances stability and resistance to nuclease degradation. This makes it valuable in creating RNA-based drugs for targeting genetic diseases, viral infections, and cancer. Its application is also significant in research for studying RNA structure, function, and interactions.