Wogonoside is widely studied for its anti-inflammatory and neuroprotective properties, making it a compound of interest in the development of treatments for neurological disorders such as Alzheimer’s and Parkinson’s disease. It has shown potential in reducing oxidative stress and inhibiting the activation of microglia, which play a role in neuroinflammation. In oncology, wogonoside exhibits antitumor activity by inducing apoptosis and cell cycle arrest in various cancer cell lines, including liver, breast, and colorectal cancers. Its ability to modulate key signaling pathways such as PI3K/AKT and NF-κB contributes to its anticancer effects. It also possesses hepatoprotective qualities, helping to protect liver cells from damage caused by toxins and inflammatory agents. This makes it a candidate for use in liver-protecting formulations or therapies targeting liver diseases. Additionally, wogonoside has been explored for its antiviral activity, particularly against viruses such as hepatitis B and influenza, due to its ability to interfere with viral replication and boost host immune responses. Due to its multiple bioactive properties, wogonoside is considered a promising lead compound in the formulation of natural product-based pharmaceuticals and functional health supplements.