tert-Butyl 4-(difluoromethyl)piperidine-1-carboxylate
97%
Reagent
Code: #151410
CAS Number
1093759-68-2
blur_circular Chemical Specifications
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Molecular Information
Weight
235.27 g/mol
Formula
C₁₁H₁₉F₂NO₂
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Registry Numbers
MDL Number
MFCD11054102
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Storage & Handling
Storage
2-8°C, Inert Gas
description Product Description
Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of central nervous system agents. Its piperidine core with a difluoromethyl group enhances metabolic stability and lipophilicity, making it valuable in drug design for improving bioavailability and blood-brain barrier penetration. Commonly employed in medicinal chemistry for optimizing lead compounds in neurodegenerative disease research and psychiatric disorder treatments. The tert-butyl carbamate (Boc) protecting group allows for selective functionalization during multi-step syntheses, enabling controlled modification of the piperidine nitrogen.
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