“pomegranate extract scope: antioxidant status and selected cardiovascular risk markers in healthy volunteers”
MultiCare™ Pomegranate Extract (Water Dispersible Ellagic Acid)
Food
Code: 254243
Water-dispersible pomegranate extract with about 9% ellagic acid for food supplement and functional beverage formulations; typical use 250-1000 mg/day ingredient, delivering about 22.5-90 mg/day ellagic acid.
MultiCare™ Pomegranate Extract (Water Dispersible Ellagic Acid) contains about 9% ellagic acid in a water-dispersible pomegranate extract format. Ellagic acid and ellagitannins are key pomegranate polyphenols, but free ellagic acid is naturally difficult to disperse in water. This product is designed to make ellagic-acid delivery easier for capsules, tablets, sachets, drink powders, beverage shots, gummies and other functional-food systems where a more uniform aqueous dispersion is needed.
| Benefit | Typical study dose* | Key human findings | High-quality sources |
|---|---|---|---|
| 1 Antioxidant & oxidative-stress support | Pomegranate extract or juice studies commonly use standardized extracts around 250 mg/day or beverage-level pomegranate polyphenol intake for several weeks. | Human pomegranate studies report improvements in antioxidant capacity and selected oxidative-stress markers. These data support antioxidant positioning, but they should not be presented as disease treatment or prevention. | PubMed 36358496 |
| 2 Cardiometabolic marker support | Pomegranate extract trials often use 250-1000 mg/day; pomegranate juice trials use food-level intake. | Clinical trials of pomegranate extract/juice show mixed but useful signals for blood pressure, lipid, inflammatory and oxidative-stress markers. The effect size depends on population, baseline risk, dose and study design. | PubMed 29152243 |
| 3 Gut microbiome & urolithin pathway | Standardized pomegranate extract 250 mg/day in a recent human microbiome study; ellagic-acid exposure varies by extract assay. | Ellagitannins release ellagic acid, which can be converted by gut microbes into urolithins. Urolithin production varies strongly between individuals, so benefits linked to this pathway may be responder-dependent. | PubMed 38201042 |
| 4 Healthy-aging and cellular-protection research | Evidence uses ellagitannin-rich foods, pomegranate extracts, ellagic acid, or urolithins; dose translation is not direct. | Mechanistic literature links ellagic acid/urolithins with redox balance, inflammatory signaling and mitochondrial-quality pathways. Human outcome evidence for ellagic acid itself remains early, so claims should be conservative. | PubMed 35142569 |
*For this ingredient, a practical shop range is 250-1000 mg/day, delivering about 22.5-90 mg/day ellagic acid from the 9% assay. Dose selection should follow the finished product format, local supplement rules and total polyphenol intake from the formula.
Mechanistic highlights
- Ellagic acid as the marker active: Ellagic acid is a low-solubility polyphenol released from pomegranate ellagitannins. The 9% assay allows formulators to calculate delivered ellagic acid per serving while using the broader pomegranate extract matrix.
- Microbiome conversion to urolithins: Ellagic acid can be metabolized by specific gut microbes into urolithins, which are more bioavailable than the parent compound. Individual urolithin-metabotype differences mean response is not uniform across all users.
- Redox and inflammatory signaling: Ellagic acid and urolithin metabolites interact with antioxidant defenses and redox-sensitive inflammatory pathways in cell and animal models, supporting cautious antioxidant and healthy-aging positioning.
- Dispersibility advantage: The water-dispersible format improves manufacturing practicality compared with conventional water-insoluble ellagic acid powders, especially in drink powders, premixes and aqueous supplement systems.
Safety & practical use
- Usual supplemental range: 250-1000 mg/day ingredient, typically 500 mg/day, supplying about 22.5-90 mg/day ellagic acid.
- Applications: Capsules, tablets, stick packs, drink powders, beverage shots, gummies, chewables and functional foods requiring a pomegranate polyphenol claim with improved aqueous dispersion.
- Formulation advice: Pre-blend with dry carriers before adding to powder systems. For beverages, disperse under moderate agitation and validate sediment, color, astringency and flavor impact in the final pH and mineral system.
- Processing limits: Protect from prolonged heat, oxygen and strong light. Polyphenols may darken, bind proteins/minerals or add astringency; run stability and sensory checks in high-protein, high-mineral or clear-beverage applications.
- Medical oversight: People using anticoagulant/antiplatelet medicines, blood-pressure or blood-glucose medicines, and pregnant or breastfeeding users should consult a healthcare professional before high-polyphenol supplementation.
- reddish brown to brown water-dispersible powder
- Room (25-40C)
- 24 Months from manufacturing or testing date.
- 250mg - 1000mg
- 500mg
- 250mg - 1000mg
- 500mg
- Powder mixing for food/beverage (oil‑phase disperse or glycol premix)
- 3.00 - 8.00
- Dispersible in water, Dispersible in powder
- Powdered Foods, Beverages, Nutrient Supplement, Dietary Supplement, Beverage Ingredient
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