GGTI-286
Reagent
Code: #108405
CAS Number
171744-11-9
blur_circular Chemical Specifications
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Molecular Information
Weight
429.58 g/mol
Formula
C₂₃H₃₁N₃O₃S
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Storage & Handling
Storage
-20°C, dry, sealed
description Product Description
GGTI-286 is primarily used in research settings to study the role of geranylgeranyltransferase I (GGTase I) in cellular processes. It acts as an inhibitor of GGTase I, which is involved in the post-translational modification of proteins, particularly those in the Rho and Rac families. By inhibiting this enzyme, GGTI-286 helps researchers understand the signaling pathways that regulate cell growth, differentiation, and survival. It is particularly useful in cancer research, as it provides insights into how inhibiting protein prenylation can affect tumor cell proliferation and metastasis. Additionally, GGTI-286 is used in studies exploring cardiovascular diseases, as GGTase I plays a role in smooth muscle cell function and vascular remodeling. Its application extends to investigating inflammatory responses and neurodegenerative diseases, where protein prenylation is a key factor. Overall, GGTI-286 serves as a valuable tool for elucidating the molecular mechanisms underlying various physiological and pathological conditions.
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GGTI-286
GGTI-286 is primarily used in research settings to study the role of geranylgeranyltransferase I (GGTase I) in cellular processes. It acts as an inhibitor of GGTase I, which is involved in the post-translational modification of proteins, particularly those in the Rho and Rac families. By inhibiting this enzyme, GGTI-286 helps researchers understand the signaling pathways that regulate cell growth, differentiation, and survival. It is particularly useful in cancer research, as it provides insights into how inhibiting protein prenylation can affect tumor cell proliferation and metastasis. Additionally, GGTI-286 is used in studies exploring cardiovascular diseases, as GGTase I plays a role in smooth muscle cell function and vascular remodeling. Its application extends to investigating inflammatory responses and neurodegenerative diseases, where protein prenylation is a key factor. Overall, GGTI-286 serves as a valuable tool for elucidating the molecular mechanisms underlying various physiological and pathological conditions.
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