CC-90009
98%
Reagent
Code: #164637
CAS Number
1860875-51-9
blur_circular Chemical Specifications
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Molecular Information
Weight
461.85 g/mol
Formula
C₂₂H₁₈ClF₂N₃O₄
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Storage & Handling
Storage
-20°C
description Product Description
Used in the treatment of acute myeloid leukemia (AML), particularly in patients with specific genetic mutations such as those involving the FLT3 gene. It functions as a targeted protein degrader, specifically designed to selectively degrade the transcription factor GSPT1, which plays a key role in protein synthesis and cell proliferation. By inducing degradation of GSPT1, the compound triggers cancer cell death while sparing normal cells to a greater extent than traditional chemotherapies. Currently investigated in clinical trials for its efficacy and safety profile, it represents a promising approach in precision oncology.
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