Fmoc-N-methyl-L-valine

98%

Reagent Code: #105128
label
Alias Fmoc-N-methyl-L-valine ; N-fluorenylmethoxycarbonyl-N-methyl-L-valine
fingerprint
CAS Number 84000-11-3

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 353.41 g/mol
Formula C₂₁H₂₃NO₄
badge Registry Numbers
MDL Number MFCD00153395
thermostat Physical Properties
Melting Point 187-190 °C
inventory_2 Storage & Handling
Storage 2~8°C

description Product Description

Fmoc-N-methyl-L-valine is widely used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS) methods. It serves as a protected amino acid derivative, where the Fmoc (fluorenylmethyloxycarbonyl) group acts as a temporary protecting group for the amine functionality. This allows for the sequential addition of amino acids to build peptides with high precision. The N-methyl group in the structure introduces steric hindrance, which can be beneficial in designing peptides with specific conformational properties or enhanced metabolic stability. This compound is especially valuable in the synthesis of complex peptides, including those used in pharmaceutical research, where controlled assembly and modification of peptide chains are critical. Its application extends to the development of peptide-based drugs, biomaterials, and probes for biochemical studies.

format_list_bulleted Product Specification

Test Parameter Specification
Appearance White To Off-White Powder
Purity (HPLC) 98-100%
Melting Point 180-190
Infrared Spectrum Conforms To Structure
Specific Rotation [α]20/D (C=1, DMF) -65 to -71 °C

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿410.00
inventory 5g
10-20 days ฿1,490.00
inventory 100g
10-20 days ฿22,960.00
inventory 25g
10-20 days ฿5,980.00
Fmoc-N-methyl-L-valine
Fmoc-N-methyl-L-valine is widely used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS) methods. It serves as a protected amino acid derivative, where the Fmoc (fluorenylmethyloxycarbonyl) group acts as a temporary protecting group for the amine functionality. This allows for the sequential addition of amino acids to build peptides with high precision. The N-methyl group in the structure introduces steric hindrance, which can be beneficial in designing peptides with specific conformational properties or enhanced metabolic stability. This compound is especially valuable in the synthesis of complex peptides, including those used in pharmaceutical research, where controlled assembly and modification of peptide chains are critical. Its application extends to the development of peptide-based drugs, biomaterials, and probes for biochemical studies.
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