Fmoc-Tyr(tBu)-OH
98%
Reagent
Code: #105137
Alias
Fluorenylmethoxycarbonyl-O-tert-butyl-L-tyrosine
CAS Number
71989-38-3
blur_circular Chemical Specifications
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Molecular Information
Weight
459.53 g/mol
Formula
C₂₈H₂₉NO₅
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Registry Numbers
EC Number
276-262-7
MDL Number
MFCD00037129
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Physical Properties
Melting Point
~150 °C (dec.)
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Storage & Handling
Storage
2~8°C
description Product Description
This chemical is widely used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). It serves as a building block for creating peptides, where the Fmoc (fluorenylmethyloxycarbonyl) group acts as a protective group for the amino group during the synthesis process. The tert-butyl (tBu) group protects the hydroxyl group of the tyrosine residue, preventing unwanted reactions. It is especially valuable in the production of complex peptides for pharmaceutical research, drug development, and biochemical studies. Its stability and ease of deprotection make it a preferred choice in automated peptide synthesizers. Additionally, it is utilized in the synthesis of peptide-based vaccines, hormones, and other therapeutic agents.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | White Crystal |
| Purity (HPLC) | 98-100 |
| Specific Rotation [a]20/D (C=1, DMF) | -32 to -28 |
| Infrared Spectrum | Conforms To Structure |
| Melting Point (°C) | 150-154 |
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