3,4,5,6-Tetrahydro-2-pyrimidinethiol is primarily utilized in organic synthesis as a key intermediate for the production of various pharmaceutical compounds. Its thiol group makes it a valuable building block for the development of drugs targeting conditions such as hypertension, cancer, and bacterial infections. Additionally, it is employed in the synthesis of heterocyclic compounds, which are essential in agrochemicals for crop protection. The compound’s reactivity also lends itself to research applications, particularly in the study of sulfur-containing molecules and their biological activities.