4-Bromo-6-fluoropyrimidine
95%
Reagent
Code: #129883
CAS Number
1209458-29-6
blur_circular Chemical Specifications
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Molecular Information
Weight
176.97 g/mol
Formula
C₄H₂BrFN₂
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Registry Numbers
MDL Number
MFCD14702771
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Physical Properties
Boiling Point
200.1±20.0 °C(Predicted)
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Storage & Handling
Density
1.838±0.06 g/cm3(Predicted)
Storage
2-8°C, Sealed, Inert Gas
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors and antiviral agents. Its halogenated pyrimidine structure allows for selective cross-coupling reactions, enabling the introduction of fluorinated aromatic systems in drug candidates. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to the electron-withdrawing effects of fluorine and the reactivity of the bromo group. Also utilized in the preparation of agrochemicals and functional materials where fluorinated heterocycles enhance stability and bioavailability.
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