4-Chloro-2-(cyclopropyl)pyrimidine-5-boronic acid
95%
science Other reagents with same CAS 2225177-67-1
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description Product Description
Used in organic synthesis as a versatile building block for the preparation of complex molecules, particularly in the pharmaceutical industry. It serves as a key intermediate in the development of drugs targeting various diseases, including cancer and infectious diseases. The boronic acid group at the 5-position enables efficient cross-coupling reactions, such as Suzuki-Miyaura reactions, to form carbon-carbon bonds, which are crucial in constructing biologically active compounds. The 4-chloro substituent facilitates nucleophilic aromatic substitution (SNAr), allowing selective introduction of diverse nucleophiles. Its pyrimidine core is a common motif in medicinal chemistry, often incorporated into molecules with therapeutic potential. Additionally, the 2-cyclopropyl group can enhance the metabolic stability and binding affinity of the final drug candidates.
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