Used as a silylating agent in organic synthesis, particularly for the protection of sensitive functional groups such as alcohols and amines during multi-step reactions. Its steric bulk enhances selectivity, making it valuable in the synthesis of complex molecules including pharmaceuticals and natural products. Commonly employed in the preparation of intermediates for agrochemicals and in the modification of silicon surfaces in semiconductor processing due to its ability to form stable monolayers. Also finds use in analytical chemistry for derivatizing polar compounds to improve volatility and detection in gas chromatography-mass spectrometry (GC-MS).