Sephacryl is widely used in biochemical laboratories for the separation and purification of biomolecules. Its primary application is in gel filtration chromatography, where it effectively separates proteins, peptides, polysaccharides, and nucleic acids based on their size. Due to its high mechanical strength and stability, it is suitable for both low-pressure and high-performance liquid chromatography (HPLC) systems. It is particularly useful in the purification of large biomolecules, such as antibodies and enzymes, as well as in the removal of aggregates or small contaminants from samples. Additionally, Sephacryl is often employed in the desalting and buffer exchange processes, ensuring optimal conditions for downstream applications like crystallization or functional studies. Its versatility and reliability make it a preferred choice in research, biopharmaceutical production, and industrial biotechnology.