Sphinganine (d20:0) is primarily utilized in biochemical and medical research due to its role as a key intermediate in the biosynthesis of sphingolipids, which are essential components of cell membranes. It is often studied for its involvement in cellular signaling pathways, particularly those related to cell growth, apoptosis, and stress responses. Researchers investigate its potential implications in diseases such as cancer, neurodegenerative disorders, and metabolic syndromes. Additionally, sphinganine is used as a biomarker to assess disruptions in sphingolipid metabolism, which can be linked to genetic disorders or toxicological effects. Its applications also extend to the development of therapeutic strategies targeting sphingolipid-related pathways.

Furthermore, sphinganine has potential applications in the cosmetics industry, where it is valued for its properties in skin repair and protection, helping to strengthen the skin barrier and maintain hydration.