Methanesulfonohydrazide is primarily used as a reagent in organic synthesis, particularly in the preparation of hydrazones and other nitrogen-containing compounds. It serves as a key intermediate in the production of pharmaceuticals, where it aids in the formation of active pharmaceutical ingredients (APIs) with specific biological activities. Additionally, it is employed in the synthesis of agrochemicals, contributing to the development of herbicides and pesticides. Its role in polymer chemistry is also notable, as it can act as a cross-linking agent or initiator in the production of specialty polymers. Furthermore, methanesulfonohydrazide is utilized in research laboratories for the development of novel chemical entities and in the study of reaction mechanisms involving hydrazide derivatives.