Polyvinylpyrrolidone K30 (PVP-K30)
Polyvinylpyrrolidone K30 (PVP-K30) is a water-soluble synthetic polymer used as a tablet binder, granulation aid, film-forming polymer, and dispersing/solubilizing excipient for food supplement and pharmaceutical solid dosage manufacturing.
This SKU is the K30 viscosity grade. The COA K value specification of 27-32 identifies the K30 grade and makes it suitable for common wet granulation, dry-binding support, and coating-assist applications where balanced binding strength, processability, and tablet disintegration are required.
PVP-K30 is used as a functional excipient. It is not positioned as a nutritional active ingredient; its role is to improve powder cohesion, granule strength, tablet hardness, film formation, and dispersion uniformity in finished supplement or pharmaceutical products.
Product Description: PVP-K30, also known as Povidone K30, is a nonionic polymer of N-vinylpyrrolidone. In tablet manufacturing, it can be used as an aqueous binder solution for wet granulation or as a dry binder in direct-compression systems. When dissolved and applied during granulation, it helps bind active ingredients and excipients into stronger granules, improving compressibility, tablet integrity, and resistance to friability.
As a film-forming polymer, PVP-K30 can support simple coating systems, granule coating, taste-masking systems, and surface-dusting reduction. It can also assist wetting and dispersion of poorly wettable powders in instant powder blends, sachets, capsules, and tablets. It is not a classical surfactant emulsifier, so dispersion benefit should be verified in the customer's actual formula.
| Application | Typical use level | Formulation purpose |
|---|---|---|
| Wet granulation binder | 0.5-5% | Improve granule strength, tablet hardness, and friability resistance. |
| Direct-compression dry binder | 1-10% | Support compact integrity when wet granulation is not used. |
| Film-forming or coating support | 2-10% | Form clear films, reduce dusting, and help carry pigments or actives in coating liquids. |
| Dispersing / wetting aid | 0.1-5% | Improve wetting and distribution of difficult powders in selected systems. |
Usage: Suitable for tablets, granules, capsules, supplement powder blends, sachets, wet granulation systems, direct-compression formulas, and simple coating or taste-masking systems.
Mixing method:
- For wet granulation, add PVP-K30 slowly into purified water under moderate stirring and mix until fully dissolved before use as a binder solution.
- Avoid dumping the full powder amount into water at once, as this can cause lumping and slow hydration.
- Typical binder-solution concentration is about 5-15% w/w, adjusted by viscosity, sprayability, granulation equipment, and target granule strength.
- For direct compression, pre-blend thoroughly with filler or the main powder phase to avoid local over-concentration.
- Optimize by tablet hardness, friability, disintegration, dissolution, granule flow, and drying performance.
Usage rate: 0.1-20%
Higher levels can increase binding strength, compact integrity, and film formation, but excessive binder may slow disintegration or dissolution, increase tackiness during granulation, and extend drying time.
Product characteristics: White to yellowish-white powder. COA specification: K value 27-32; moisture max 5%; pH 3-7 at 5% in water; N-vinylpyrrolidone max 0.1%; residue on ignition max 0.1%; nitrogen 11.5-12.8%; heavy metals as Pb max 10ppm.
Solubility: Soluble in water. Suitable for aqueous binder solutions and selected hydroalcoholic systems, depending on solvent ratio, regulatory requirements, and finished product type.
Storage: Store tightly closed in a dry area. Protect from moisture and avoid prolonged exposure to air to maintain powder flow and binder performance.
- Room (25-40C)
- 24 Months from manufacturing or testing date.
- Add into water phase. Heat tolerant.
- Avoid heat above 80C
- 3.50 - 9.00
- Soluble in Water, Soluble in glycols, Soluble in Ethanol, Dispersible in water, Soluble in DMSO (Dimethyl Sulfoxide)
- › PVP
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| Test Name | Specification |
|---|---|
| K Value | 27-32 |
| Moisture | 5% Max |
| pH (5% in water) | 3-7 |
| N-vinylpyrrolidone | 0.1% Max |
| Residue on Ignition | 0.1% Max |
| Nitrogen | 11.5-12.8% |
| Heavy Metals (as Pb) | 10ppm Max |
| Acetaldehyde (ppm) | 500ppm Max |
| Hydrazine | 1ppm Max |
| Peroxide | 400ppm Max |
| Appearance | White or yellowish-white powder |
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