5-(4-Bromophenyl)-1H-tetrazole
≥97%
Reagent
Code: #173763
CAS Number
50907-23-8
blur_circular Chemical Specifications
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Molecular Information
Weight
225.05 g/mol
Formula
C₇H₅BrN₄
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Registry Numbers
MDL Number
MFCD00991874
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of sartan-class antihypertensive drugs such as valsartan and losartan. Its tetrazole ring serves as a bioisostere for the carboxylic acid group, enhancing metabolic stability and improving binding affinity to the angiotensin II receptor. Also employed in coordination chemistry as a ligand for metal ions in catalytic systems. Additionally, it finds use in the development of functional materials and in click chemistry due to its ability to participate in cycloaddition reactions.
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