Used primarily in organic synthesis, 2,4,6-Trimethoxybenzenethiol serves as a key building block for creating complex molecules. It is often employed in the development of pharmaceuticals, where its structure aids in the formation of sulfur-containing compounds. Additionally, it finds application in material science, particularly in the synthesis of polymers and coatings, where its thiol group enables cross-linking reactions. Its methoxy groups also make it useful in the preparation of ligands for catalytic systems, enhancing their stability and reactivity.