4-Bromo-5-chlorothiophene-2-carboxylic acid
96%
Reagent
Code: #148756
CAS Number
60729-37-5
blur_circular Chemical Specifications
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Molecular Information
Weight
241.49 g/mol
Formula
C₅H₂BrClO₂S
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Registry Numbers
MDL Number
MFCD00847582
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Storage & Handling
Storage
2-8°C, protected from light, stored in inert gas
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in the development of thiophene-based bioactive molecules. Its functional groups, including bromine, chlorine, and carboxylic acid, allow for selective modifications such as nucleophilic substitutions and palladium- or copper-catalyzed cross-coupling reactions for carbon-carbon bond formation, making it valuable in constructing complex organic compounds in fewer steps. Commonly employed in the preparation of antifungal, antibacterial, and anti-inflammatory agents. Also utilized in the manufacture of specialty polymers and electronic materials due to the electron-rich nature of the thiophene ring.
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