tert-Butyl ((1H-benzo[d][1,2,3]triazol-1-yl)methyl)carbamate
97%
Reagent
Code: #192954
CAS Number
305860-41-7
science Other reagents with same CAS 305860-41-7
blur_circular Chemical Specifications
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Molecular Information
Weight
248.28 g/mol
Formula
C₁₂H₁₆N₄O₂
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Registry Numbers
MDL Number
MFCD01924426
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Physical Properties
Boiling Point
419.9±28.0 °C(Predicted)
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Storage & Handling
Density
1.23±0.1 g/cm3(Predicted)
Storage
2-8°C, Sealed, Inert Gas
description Product Description
Used as a protected amine building block in peptide synthesis and medicinal chemistry. The tert-butyl carbamate (Boc) group provides stability under various reaction conditions while the benzotriazole moiety acts as a good leaving group, facilitating amide bond formation or nucleophilic substitution. Commonly employed in the preparation of protease inhibitors, kinase inhibitors, and other bioactive molecules where controlled deprotection and coupling are required. Also utilized in solid-phase synthesis and combinatorial chemistry due to its compatibility with a wide range of functional groups and protecting group strategies.
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