Lipase G derived from Penicillium sampson is widely used in industrial and biotechnological applications due to its high catalytic efficiency and stability under various conditions. It is commonly employed in the food industry for flavor development in dairy products, particularly in cheese ripening, where it enhances aroma and taste by breaking down milk fats. In the biodiesel sector, this enzyme catalyzes the transesterification of triglycerides into fatty acid methyl esters, offering a greener alternative to chemical catalysts. It is also utilized in the synthesis of esters for cosmetics and pharmaceuticals, enabling selective reactions under mild conditions. Additionally, Lipase G finds application in leather processing to remove fats from hides and in detergent formulations to degrade oily stains, improving cleaning performance at lower temperatures.