Used in solid-phase peptide synthesis as a protected building block for incorporating constrained amino acid residues into peptide chains. The Fmoc group allows for orthogonal protection, enabling stepwise assembly under mild basic conditions. The ketone functionality in the cyclohexyl ring provides a site for further chemical modification, such as oxime or hydrazone formation, useful in peptide conjugation, labeling, or macrocyclization strategies. Its rigid cyclic structure introduces conformational restraint, aiding in the design of peptidomimetics and bioactive peptide analogs with improved stability or receptor selectivity.