N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-O-ethyl-N-methyl-L-serine
98%
science Other reagents with same CAS 1931107-98-0
blur_circular Chemical Specifications
description Product Description
This compound is a protected derivative of N-methyl-L-serine, serving as a key building block in solid-phase peptide synthesis. The Fmoc group temporarily protects the N-methyl alpha-amino functionality, allowing selective deprotection under mild basic conditions (e.g., piperidine) for stepwise peptide assembly. The serine side chain hydroxyl is protected as an ethyl ether (O-ethyl), providing stability during basic deprotection and coupling steps, while being removable under acidic or other specific conditions later in the synthesis. The free carboxylic acid enables efficient amide bond formation. It is particularly valuable for incorporating N-methylserine residues into complex peptides with high purity and yield, commonly used in biochemical research, drug discovery, and pharmaceutical development for bioactive peptides and assays.