Used in bioconjugation to link biomolecules such as peptides, proteins, or antibodies through thiol groups. The maleimide groups react specifically with thiols to form stable thioether bonds, enabling controlled drug delivery systems and protein modification. Frequently applied in creating hydrogels for tissue engineering due to its multi-arm structure, which allows crosslinking into three-dimensional networks. Also utilized in PEGylation to improve the stability and solubility of therapeutic compounds while reducing immunogenicity. Common in pharmaceutical research and development of biocompatible materials.