(R)-1-(4-Chloro-3-Fluorophenyl)Ethane-1,2-Diol
95%
science Other reagents with same CAS 1453854-84-6
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description Product Description
Used as a chiral intermediate in the synthesis of pharmaceuticals, particularly in the production of beta-blockers, cardiovascular drugs, CNS agents, and anti-inflammatory compounds. Its R-stereochemistry allows for selective biological activity, making it valuable in asymmetric synthesis. The structure features two hydroxyl groups along with both fluorine and chlorine substituents on the phenyl ring, enabling versatile reactivity such as ether bond formation, nucleophilic substitution, or cyclization. Also employed in the development of fluorinated organic compounds where enhanced metabolic stability and membrane permeability are desired. Commonly utilized in research settings for designing bioactive molecules, as the substituents influence binding affinity, pharmacokinetics, and stereochemical control to improve efficacy and reduce side effects.
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