1-(3,4,5-trifluorophenyl)cyclopropan-1-amine hydrochloride
98%
science Other reagents with same CAS 1248300-11-9
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description Product Description
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of fluorinated analogs of bioactive molecules. Its rigid cyclopropane scaffold combined with fluorinated aromatic substitution enhances metabolic stability and binding selectivity, making it valuable in medicinal chemistry for CNS-targeted drugs and kinase inhibitors. The amine functionality allows for facile derivatization, enabling incorporation into larger molecular architectures for structure-activity relationship studies. Also employed in the preparation of fluorinated building blocks for PET tracer development due to the presence of multiple fluorine atoms that can aid in imaging applications.
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