Z-D-allo-Thr(tBu)-OH DCHA
Reagent
Code: #246405
CAS Number
100157-55-9
science Other reagents with same CAS 100157-55-9
blur_circular Chemical Specifications
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Molecular Information
Weight
490.68 g/mol
Formula
C₂₈H₄₆N₂O₅
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Storage & Handling
Storage
-20°C
description Product Description
Used as a chiral building block in the synthesis of complex peptides and pharmaceuticals, particularly in solid-phase peptide synthesis where stereochemical control is critical. Its tert-butyl protected side chain ensures stability under various reaction conditions, while the dicyclohexylamine (DCHA) salt form enhances crystallinity and handling properties. Commonly employed in the preparation of enzyme inhibitors and bioactive molecules requiring specific stereochemistry. The Z (benzyloxycarbonyl) group allows for selective deprotection, enabling stepwise assembly of peptide chains without racemization.
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