Used in the treatment of neuropathic pain, particularly osteoarthritis knee pain. Acts as a transient receptor potential vanilloid 1 (TRPV1) agonist, modulating pain signaling pathways. Applied topically, it helps desensitize nerve fibers over time, reducing pain perception without significant systemic absorption. Offers an alternative to oral pain medications with potentially fewer side effects. Currently investigated for other chronic pain conditions due to its targeted mechanism of action.