6-(t-butyldimethylsiloxy)-3,4-dihydro-2H-pyran

97%

Reagent Code: #191848
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CAS Number 130650-09-8

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 214.377 g/mol
Formula C₁₁H₂₂O₂Si
badge Registry Numbers
MDL Number MFCD00134551
thermostat Physical Properties
Boiling Point 125-131 °C at 28 mmHg(lit.)
inventory_2 Storage & Handling
Storage 2-8°C

description Product Description

Used as a protected form of 6-hydroxy-3,4-dihydro-2H-pyran in organic synthesis, particularly in the preparation of complex natural products and pharmaceuticals. The t-butyldimethylsiloxy (TBS) group acts as a robust protecting group for alcohols, offering stability under a variety of reaction conditions while being selectively removable with fluoride reagents. This compound is valuable in multi-step syntheses where chemoselectivity and functional group compatibility are critical, such as in the construction of polyketide-like structures or carbohydrate derivatives. Its cyclic enol ether structure also allows for controlled ring-opening or functionalization reactions, making it a versatile building block in synthetic routes.

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿23,010.00
6-(t-butyldimethylsiloxy)-3,4-dihydro-2H-pyran
Used as a protected form of 6-hydroxy-3,4-dihydro-2H-pyran in organic synthesis, particularly in the preparation of complex natural products and pharmaceuticals. The t-butyldimethylsiloxy (TBS) group acts as a robust protecting group for alcohols, offering stability under a variety of reaction conditions while being selectively removable with fluoride reagents. This compound is valuable in multi-step syntheses where chemoselectivity and functional group compatibility are critical, such as in the construction of polyketide-like structures or carbohydrate derivatives. Its cyclic enol ether structure also allows for controlled ring-opening or functionalization reactions, making it a versatile building block in synthetic routes.
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