Bakuchiol EZ™ (Water-Soluble Bakuchiol 15%)
15% water‑soluble bakuchiol concentrate—retinol‑like endpoints with softer tolerability; easy addition to water‑based formulas.
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15% water‑soluble bakuchiol concentrate—retinol‑like endpoints with softer tolerability; easy addition to water‑based formulas.
Bakuchiol EZ (Water-Soluble Bakuchiol 15%) is a water‑soluble bakuchiol concentrate standardized at 15% active. It delivers retinol‑like endpoints (lines, tone, texture) with generally softer tolerability, and is engineered for straightforward use in water‑based skincare.
Bakuchiol, a plant‑derived meroterpene, has been shown to modulate retinol‑like gene expression in skin (↑ collagen I/III/IV; ↑ aquaporin‑3) and to provide antioxidant/anti‑inflammatory support. Clinical data report wrinkle and pigment improvements comparable to retinol with fewer irritation symptoms.
This 15% format dissolves the active in a water‑compatible carrier (glycol + non‑ionic surfactant) to improve handling, clarity, and day‑use practicality versus pure oil‑soluble bakuchiol. Delivered‑active drives performance—dose the concentrate so the on‑skin % bakuchiol lands in your target range.
Product Description: Bakuchiol supports extracellular‑matrix integrity through retinol‑like transcriptional effects (e.g., collagen I/III/IV) and anti‑oxidative/anti‑inflammatory pathways linked to smoother texture, reduced wrinkle appearance, and more even tone. In a 12‑week randomized, double‑blind trial, 0.5% bakuchiol applied twice daily performed similarly to 0.5% retinol nightly for wrinkles and hyperpigmentation, with lower reports of stinging/scaling. Independent reviews highlight daytime suitability/photostability and improved tolerability relative to retinoids.
| Model/System | Key Endpoints | Implication |
|---|---|---|
| 12‑week clinical RCT (0.5% bakuchiol bid vs 0.5% retinol qhs) | Similar wrinkle/pigment gains; fewer stinging/scaling reports with bakuchiol | Retinol‑like outcomes, softer tolerability |
| Clinical + gene‑expression profiling | ↑ collagen I/III/IV; ↑ AQP‑3; antioxidant/anti‑inflammatory signals | Texture/firmness/pigment support |
| Stability/photostability (analytical, cosmetic matrices) | Content typically within ±5% after thermal/photolytic stress | Daytime‑suitable (pair with SPF) |
| Layering/combination (emerging) | May complement retinoids (e.g., retinal); monitor skin response | Flexibility in advanced routines |
Usage: Leave‑on anti‑aging formats (serums, creams, lotions, gels). Often layered with antioxidants (vitamin C/E), niacinamide, peptides, sunscreen. Can be used day and night; when pairing with retinoids, introduce gradually and monitor.
Mixing method:
- Add during cool‑down (<40°C) into the water or water/glycol phase, or post‑emulsification.
- Surfactant systems (cleansers): add slowly under gentle stirring; verify clarity/foam profile; avoid strong oxidants.
- pH ~4–8. For clear gels/serums, check compatibility with electrolytes/cationic polymers (high ionic strength may cause haze).
Usage rate: Use 3–10% of this concentrate to deliver ~0.45–1.5% bakuchiol active. Examples: 3% → ~0.45%; 5% → ~0.75% (typical); 10% → ~1.5%.
Product characteristics: Clear to slightly hazy, pale‑yellow liquid; low viscosity; mild characteristic odor; stabilized with antioxidant/preservative.
Solubility: Water‑soluble concentrate; freely soluble in glycols; miscible into aqueous and surfactant bases; not intended for anhydrous oil systems without co‑solvents.
Storage: Store tightly closed at room temperature; protect from light and air; do not heat above 40°C.
Notes: Patch test if sensitive; discontinue if irritation occurs. Pregnancy/lactation—bakuchiol is not a retinoid but human data are limited; advise caution. Daytime use should include broad‑spectrum SPF.
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