“Polysorbate 80 interacted with a stratum-corneum lipid model, supporting its mechanism as a nonionic surfactant skin penetration enhancer; evidence is mechanistic/model-based rather than clinical skin benefit evidence.”
Polysorbate 80 (Tween 80)
Cosmetics
Code: 176
High HLB emulsifier
Polysorbate 80 (Tween 80) - high purity / cosmetic grade
Difference between Polysorbate 20, Polysorbate 80
Polysorbate 80 is soluble in oil, water, but not soluble in Glycerin.
Polysorbate 20 is soluble in water, Glycerin, but incompletely soluble. (turbidity) in the oil
Polysorbate 80 has a higher weight/thickness and HLB value than Polysorbate 20.
In case if you need clear/colorless high HLB solubilizer, please use Flora Solve Clear, colorless solubilizer instead.
Usage rate: 1-20%
Product characteristics: Clear, slightly thick, golden yellow liquid.
Solubility: Can be dissolved in water/oil.
INCI Name : Polysorbate 80
- Clear to slightly yellow viscous liquid
- Room (25-40C)
- 24 Months from manufacturing or testing date.
- 0.10% - 5.00%
- 0.00%
- Add into water phase. May heat 70-80C to increase solubility
- Avoid heat above 80C
- 0.00 - 0.00
- Soluble in Water, Soluble in Oil, Soluble in glycols, Soluble in Ethanol
- Cream, Lotion, Liquid Soap, Shampoo, Conditioner, Cleanser, Foundation, Sun Screen, Body Butter
- -
| Test Name | Specification |
|---|---|
| Appearance | Light yellow to yellow oily liquid |
| Colour Lovibond (R/Y) | ≤1.5R 10Y |
| Acid Value (mg KOH/g) | ≤2.0 |
| Saponification Value (mg KOH/g) | 45-55 |
| Hydroxyl Value (mg KOH/g) | 65-80 |
| Residue on Ignition (w%) | ≤0.25 |
| Water (w%) | ≤3.0 |
| Lead (mg/kg) | ≤2 |
| Arsenic (mg/kg) | ≤3 |
| Oxyethylene (w%) | 65.0-69.5 |
“Polysorbate 80 was evaluated as a dermal-emulsion stabilizer and showed comparatively favorable compatibility with primary human skin cells under UVA exposure; this supports skin-friendly emulsifier use rather than an active skin-care benefit.”
“Tween 80-based mixed micelles improved transdermal delivery of valsartan in ex vivo/in vivo models; this supports Polysorbate 80 as a topical/transdermal delivery excipient, not as a direct cosmetic active.”
“A transdermal formulation study used Tween 80 as a penetration enhancer and optimized permeation/adhesion responses, supporting ingredient-family evidence for delivery enhancement through skin.”
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