Prebio-Man (D-Mannose Skin Prebiotic)
a natural sugar found in many plants and fruits, has shown remarkable benefits for skin health. Studies reveal that applying D-Mannose to the skin can significantly reduce symptoms of atopic dermatitis (a type of eczema) and inflammation
D-Mannose, a natural sugar found in many plants and fruits, has shown remarkable benefits for skin health. Studies reveal that applying D-Mannose to the skin can significantly reduce symptoms of atopic dermatitis (a type of eczema) and inflammation. It works by blocking specific pathways (mTOR/NF-κB) that cause inflammation, thereby restoring the skin's barrier function and reducing redness and itching.
Reference:
https://doi.org/10.1016/j.intimp.2022.109378
D-Mannose ameliorates DNCB-induced atopic dermatitis in mice and TNF-α-induced inflammation in human keratinocytes via mTOR/NF-κB pathway
Usage: For any product
Mixing method: Mix in water (water-phase)
Rate of use: 1-3% (recommended 3%)
Product characteristics: White powder
Solubility: Soluble in water
Storage: If you want to keep long-term Keep in a cool place Do not be exposed to sunlight When the lid is opened and closed immediately And seal tightly Beware of humidity Be at least 2 years old
INCI Name : Mannose
Examples of products used
La Roche Posay Cicaplast Baume B5+
- Room (25-40C)
- 36 Months from manufacturing or testing date.
- 0.10% - 5.00%
- 3.00%
- Add into water phase. Heat tolerant.
- Avoid heat above 80C
- 4.00 - 10.00
- Soluble in Water
- Cream, Lotion, Serum
- › Mannose
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| Test Name | Specification |
|---|---|
| Appearance | White or almost white crystalline powder, no odor,freely soluble in water, no observable impurities |
| D-Mannose Content | 99% Min |
| Loss on drying | 0.5% Max |
| Residue on ignition | 0.1% Max |
| Specific Rotation | +13.3 to +14.7 |
| Melting Point (C) | 126-136 |
| Appearance of solution | Clear |
| Chloride (CI-) | 0.005% Max |
| Sulfate (SO4 2-) | 0.005% Max |
| Pb | 0.5mg/kg Max |
| Total bacteria count | 1000CFU/g Max |
| Yeasts and Molds | 100CFU/g Max |
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