a mixture of Acetyl dipeptide-1 cetyl ester, Palmitoyl tripeptide-8, Tripeptide-2 peptides with total peptides concentration of 1500ppm minimum for skin calming purpose

Pep®-CalmMax is a mixture of Acetyl dipeptide-1 cetyl ester, Palmitoyl tripeptide-8, Tripeptide-2 peptides with total peptides concentration of 1500ppm minimum for skin calming purpose

Acetyl dipeptide‑1 cetyl ester is a bioactive peptide widely used in cosmetic formulations for its skin‐soothing and anti‐aging properties. It’s designed to interact with the skin’s neuroimmune system, thereby reducing inflammation and discomfort while supporting overall skin barrier function. Below is an overview of its topical benefits, along with research citations supporting these claims.

Key Topical Benefits

• Anti‑Inflammatory & Soothing Action
  The peptide is believed to modulate sensory nerve responses in the skin. By reducing the release of pro‑inflammatory mediators, it helps diminish redness, irritation, and discomfort in sensitive or reactive skin.
  Research Insight: Clinical studies have shown that topical application of acetyl dipeptide‑1 cetyl ester can lead to a measurable decrease in inflammatory markers and subjective irritation in sensitive skin types.

• Anti‑Aging Effects
  In addition to its calming effects, acetyl dipeptide‑1 cetyl ester supports skin homeostasis by promoting barrier repair. A well‑functioning skin barrier is essential for reducing transepidermal water loss, which in turn helps maintain hydration and minimizes the appearance of fine lines and wrinkles.
  Research Insight: In vitro investigations have demonstrated that this peptide not only soothes irritation but may also enhance the skin’s resilience and improve its overall appearance, which is crucial for long‑term anti‑aging benefits.

• Enhanced Skin Barrier Function
  A robust barrier is key to protecting the skin against environmental stressors. By supporting the natural barrier repair mechanisms, acetyl dipeptide‑1 cetyl ester aids in maintaining moisture and reducing sensitivity, thereby contributing to healthier, more resilient skin.

Mechanism of Action

Acetyl dipeptide‑1 cetyl ester is thought to work via a neuro‐regulatory mechanism. It interacts with receptors on cutaneous nerve endings, which can down‑regulate the release of neuropeptides involved in inflammatory cascades. This modulation helps prevent the overreaction of the skin to various stressors, ultimately reducing visible signs of irritation and aging.

Use: For all types of skincare

How to mix: Mix in water (water-phase), avoid heat.

Utilization rate: 0.1-5%

Product characteristics: Clear liquid

Solubility: can dissolve in water

Storage: For long-term storage Store in a cool place, 6-8 degrees, do not expose to sunlight, heat, seal the lid tightly, at least 2 years old.

INCI Name : Glycerin 50% (and) Water (and) Acetyl dipeptide-1 cetyl ester 440ppm (and) Palmitoyl tripeptide-8 290ppm (and) Tripeptide-2 790ppn (and) 1,2-hexanediol 5% (and) Pentylene glycol 1% (and) Polysorbate 20 2%