Pep®-Coll (Palmitoyl tripeptide-5)

Cosmetics Code: 50

Peptides are designed to stimulate the skin to produce natural collagen. They are developed from small peptides that are effective in reducing wrinkles on all types of skin. Research has confirmed that they can effectively reduce wrinkles in a short period of time.

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Pep®-Coll is a peptide designed to stimulate the skin to produce collagen through natural processes. It is developed from small peptides that are effective in reducing wrinkles on all types of skin.

Pep®-Coll has been proven by research to increase collagen production and effectively reduce wrinkles in a short period of time.

Usage: For wrinkle reducing products, in the form of gel, serum, lotion or cream.

Mixing method: Shake before use. mix at the last step. The temperature of the cosmetic must be below 40 ° C.

Usage rate: 1-5% (recommended 3%)

Product appearance: Colorless liquid

Solubility: Soluble in water.

INCI Name : Palmitoyl tripeptide-5, glycerin

Preservative-free

In a trial conducted on 60 subjects using Pep®-Coll at a concentration of 2.5% for 84 days, twice daily, most showed a significant reduction in wrinkles . *Results depend on individual skin type (please see the brochure for more details on the trial results).

If the skin depth analysis was performed, wrinkles were clearly reduced after 84 days.

The experimental results found that when comparing the efficacy of Matrixyl, Pep®-Coll was found to be significantly more effective in reducing wrinkles in all 3 dimensions (width, length, depth) with an efficacy between 25-60%.

*Results depend on each person's skin.

Examples of products used:

Paula's Choice Resist Super Antioxidant Concentrate (Serum)

Dermalogica Antioxidant Hydrating Mist

Murad Active Radiance® Serum


  • China
  • China
    • -
    Test Name Specification
    Appearance Clear to slightly opaque, colorless liquid
    Palmitoyl tripeptide-5 Content 950-1200ppm
    Total Aerobic Microbial Count < 100 CFU/ml
    Total Yeast and Mold Count < 10 CFU/ml
    Escherichia Coli Not detected

    “Direct Palmitoyl Tripeptide-5 family evidence: topical peptides review describes Palmitoyl Tripeptide-5 as a thrombospondin-mimetic signal peptide linked to TGF-β activation and reports an 84-day controlled trial showing reduced wrinkle appearance versus placebo/comparator creams.”
    Pai VV, Bhandari P, Shukla P Topical peptides as cosmeceuticals
    “Direct ingredient-family evidence: Palmitoyl Tripeptide-5 is described as a cosmetic peptide that stimulates TGF-β-related collagen biosynthesis and inhibits collagen-degrading MMPs, supporting firmness and elasticity claims; mostly mechanistic/review-level evidence.”
    Errante F, Ledwoń P, Latajka R, Rovero P, Papini AM Cosmeceutical Peptides in the Framework of Sustainable Wellness Economy


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    Pep®-Coll (Palmitoyl tripeptide-5)

    Peptides are designed to stimulate the skin to produce natural collagen. They are developed from small peptides that are effective in reducing wrinkles on all types of skin. Research has confirmed that they can effectively reduce wrinkles in a short period of time.

    Pep®-Coll is a peptide designed to stimulate the skin to produce collagen through natural processes. It is developed from small peptides that are effective in reducing wrinkles on all types of skin.

    Pep®-Coll has been proven by research to increase collagen production and effectively reduce wrinkles in a short period of time.

    Usage: For wrinkle reducing products, in the form of gel, serum, lotion or cream.

    Mixing method: Shake before use. mix at the last step. The temperature of the cosmetic must be below 40 ° C.

    Usage rate: 1-5% (recommended 3%)

    Product appearance: Colorless liquid

    Solubility: Soluble in water.

    INCI Name : Palmitoyl tripeptide-5, glycerin

    Preservative-free

    In a trial conducted on 60 subjects using Pep®-Coll at a concentration of 2.5% for 84 days, twice daily, most showed a significant reduction in wrinkles . *Results depend on individual skin type (please see the brochure for more details on the trial results).

    If the skin depth analysis was performed, wrinkles were clearly reduced after 84 days.

    The experimental results found that when comparing the efficacy of Matrixyl, Pep®-Coll was found to be significantly more effective in reducing wrinkles in all 3 dimensions (width, length, depth) with an efficacy between 25-60%.

    *Results depend on each person's skin.

    Examples of products used:

    Paula's Choice Resist Super Antioxidant Concentrate (Serum)

    Dermalogica Antioxidant Hydrating Mist

    Murad Active Radiance® Serum

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