Safe-B3™ (Vitamin B3, Niacinamide)
reduce wrinkles Reduce redness / blackness (hyperpigment), add moisture. By stimulating the skin to produce collagen and ceramide (ceramide) and also make the skin strong. Fights irritations (irritants) better. It can also reduce oiliness on the face (sebum excretion).
type ultra high purity That can be used at a rate of 10% without Flushing (allergic/redness) compared to the normal type.
Niacinamide or Vitamin B3 type Safe-B3™ have ultra high purity That can be used at a rate of 10% without Flushing (allergic/redness) compared to the normal type. At a usage rate of more than 5%, there will be symptoms of Flushing or redness on the skin.
Vitamin B3 is a vitamin that is beneficial to the skin. especially to reduce wrinkles Reduce redness / blackness (hyperpigment), add moisture. By stimulating the skin to produce collagen and ceramide (ceramide) and also make the skin strong. Fights irritations (irritants) better. It can also reduce oiliness on the face (sebum excretion), suitable for acne-prone skin.
Vitamin B3 has the effect of increasing blood flow. Therefore, it can be used to correct dark circles around the eyes. due to dark circles around the eyes Caused by fanaticism or low blood flow in the area causing a darker color
Research Paper About Niacinamide Benefits on skin:
Improving Skin Barrier Function and Reducing Transepidermal Water Loss (TEWL): "Nicotinamide is a Safe, Well-Tolerated Topical Treatment for Strengthening the Skin Barrier" by Bissett et al., published in the International Journal of Cosmetic Science (2021).
Reducing Hyperpigmentation and Improving Skin Tone: "Topical Nicotinamide: A Review of Molecular Actions and Clinical Applications in Skin Hyperpigmentation" by Kuloğlu et al., published in the Journal of Cosmetic Dermatology (2021).
Anti-Inflammatory and Anti-Aging Effects: "The Potential Role of Niacinamide in Protecting Skin from Environmental Stressors" by Bissett et al., published in the Journal of Cosmetic Dermatology (2022).
Improving Acne and Sebum Control: "Topical Nicotinamide: A Review of Molecular Actions and Clinical Applications in Acne" by Kuloğlu et al., published in the Journal of Dermatological Treatment (2020).
Enhancing Skin Hydration and Improving Texture: "Nicotinamide Enhances the Hydrating Effects of a Moisturizing Formulation" by Bissett et al., published in the Journal of Cosmetic Dermatology (2020).
Use: For products to reduce wrinkles, whitening to clear skin. and help against acne It is in the form of a gel, serum, lotion or cream.
Mixing method: Mix in water (water-phase) with heat resistance. But should not be heated for a long time and the optimum pH is in the range of 3-8 (best at 4.0-7.0).
Usage rate: 1-10% (recommended 5%, Safe-B3 type can be used up to 10% without causing allergy or skin irritation)
Product characteristics: White powder
Solubility: can dissolve in water
- › ต้านอนุมูลอิสระ (Anti-oxidant, Free-radical Scavenging)
- › ลดการระคายเคือง (Anti-irritant / Skin-Barrier Restoration)
- › ลดการสร้างเม็ดสี (Whitening - Tyrosinase Activity Inhibition)
- › ลดการสร้างเม็ดสี (Whitening - Keratinocyte/Melanocyte Signaling Inhibition)
- › ลดความมันผิว (Sebum Reducing - 5-alpha reductase inhibition)
- › ให้ความชุ่มชื้น (Moisturizing - Structure Replenishing)
- › ลดการสร้างเม็ดสี (Whitening - Inhibiting Melanosomes Transfer)
- › ลดการอักเสบ (Prostaglandin E2/COX-2 Inhibition)
- Room (25-40C)
- 60 Months from manufacturing or testing date.
- 0.10% - 10.00%
- 5.00%
- Add into water phase. Avoid temperature above 60C.
- Avoid heat above 80C
- 3.00 - 8.00
- Soluble in Water, Soluble in glycols, Soluble in Ethanol, Dispersible in cream or gel base
- Cream, Lotion, Clear Gel, Toner, Mask, Cleanser, Foundation, Primer, Concealer, Sun Screen
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| Test Name | Specification |
|---|---|
| Description and Solubility | White crystalline powder. |
| Identification Test (A) IR | Freely soluble in water and in alcohol; soluble in glycerin. The IR Absorption spectrum is concordant with the spectrum of refe |
| Identification Test (B) UV | 0.63 - 0.67 |
| Assay (by HPLC) | 98.5%w/w - 101.5 %w/w |
| Residue on Ignition | NMT 0.1%w/w |
| Readily Carbonizable Substance | Test as per UPS |
| Melting Range | 128 to 131C |
| Loss on Drying | NMT 0.5% w/w |
| Niacin content | NMT 100 ppm |
| Heavy Metals | NMT 30 ppm |
| pH | 6.0 - 7.5 |
Recommend Lab-Service
| scienceLab Service | Price |
|---|---|
open_in_newHPLC Analysis of Niacin impurities in NiacinamideMeasure niacin content in finished product to make sure the finished product will not cause flushing effect on skin. | ฿ 2,990.00 |