“Ingredient-family evidence: topical HA improves skin hydration, elasticity, firmness, roughness, and wrinkle appearance in clinical/cosmeceutical studies.”
Hyaluronic Acid (Japan)
Cosmetics
Code: 6309
Japanese Sodium Hyaluronate powder for clear premium hydrating gels and serums, with easy water dissolution and refined skin feel.
Hyaluronic Acid (Japan) is a Japanese sodium hyaluronate powder for premium water-based cosmetic formulas.
This grade is selected for easy water dissolution, very clear gel appearance and a refined skin feel compared with routine sodium hyaluronate powders.
It is suitable when clarity, processing ease and Japanese quasi-drug ingredient standard positioning are important.
Product Description: The material is produced by Streptococcus zooepidemicus fermentation and meets JSQI (Japanese Standard of Quasi-Drug Ingredients) style quality positioning. The old processing note that it can be stirred by hand until clear in about 15 minutes is kept as practical formulation guidance.
This grade has a narrower pH character around 6-7 and gives very clear solution/gel appearance with transmission above 98%. Use it when a formula needs clean transparency and a premium hydrated skin feel.
Usage: Suitable for clear hydrating gels, serums, essences, lotions, creams, sheet-mask serum and Japanese-style hyaluron gel products.
Mixing method:
- Disperse into room-temperature water and mix until fully clear. Small batches may be stirred by hand, but mechanical mixing is faster and more consistent.
- Avoid adding the powder as a lump. Sprinkle gradually into moving water.
- Keep final formula around mildly acidic to neutral pH; this grade is best around pH 6-7.
Usage rate: 0.1-1.0%.
Product characteristics: White to pale yellow powder with slight characteristic odor.
Solubility: Water soluble; dissolves more easily than many routine HA powders.
Storage: Keep tightly closed in a cool, dry place away from heat and sunlight.
INCI Name: Sodium Hyaluronate
- Cool (15-25C)
- 18 Months from manufacturing or testing date.
- 0.10% - 1.00%
- 1.00%
- Add into water phase. Avoid temperature above 60C.
- Avoid heat above 60C
- 3.00 - 9.00
- Soluble in Water
- Cream, Lotion, Clear Gel, Toner, Mask, Scrub
- -
| Test Name | Specification |
|---|---|
| Description | White to pale yellow powder, having a slight, characteristic odor. |
| Identification (1) Reaction with CPC | - |
| Identification (2) Sodium | - |
| Identification (3) Glucuronic acid | - |
| pH | 6.0-7.0 |
| Purity (1) Heavy metals | Not more than 20 ppm |
| Purity (2) Arsenic | Not more than 2 ppm |
| Purity (3) Protein | Not more than 0.1 % |
| Purity (4) Presence of the other mucopolysaccharides | None detected |
| Purity (5) Hemolytic streptococcus | - |
| Purity (6) Hemolysis | A red blood corpuscle is precipitated and the top of the solution is clear. |
| Loss on drying | Not more than 10.0 % |
| Residue on ignition | 15.0~20.0 % |
| Assay (1) Nitrogen | 3.0~4.0 % |
| Assay (2) Glucuronic acid | 40.0~50.0 % |
| Intrinsic viscosity | 19.5~32.0 dL/g |
| Bacterial test (1) Aerobic plate counts | Not more than 100 /g |
| Bacterial test (2) E.coli | Negative |
| Bacterial test (3) Mold and yeast | Not more than 100 /g |
“Ingredient-family evidence: a topical HA serum improved skin plumpness, hydration, smoothness, and fine-line appearance in a clinical facial study.”
“Molecular-weight evidence: HA of different molecular weights can penetrate skin differently, supporting use of mixed-size HA systems for multi-level hydration claims.”
“Ingredient-family evidence: topical low-molecular-weight HA was more effective than high-molecular-weight HA for improving aging-skin hydration in a systematic review/meta-analysis.”
“Multi-weight HA formulation evidence: daily use of multi-weight HA moisturizers improved skin hydration and overall skin-health appearance in clinical testing.”
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